EP-1293: Intensified neo-adjuvant chemoradiotherapy in locally advanced rectal cancer: long-term follow-up
نویسندگان
چکیده
منابع مشابه
Intensified neoadjuvant radio-chemotherapy for locally advanced rectal cancer: mono-istitutional experience and long-term results
Background: Purpose: The purpose of our study is to demonstrate that intensified neoadjuvant chemo-radiotherapy (CRT) treatment in locally advanced rectal cancer (LARC), aimed at further enhancing the complete pathological response and local disease control, is feasible and well tolerated. Materials and Methods: From January 2011 to December 2015, 62 patients (women 21, men 41, mean age 61,5, ...
متن کاملCurrent Status of Intensified Neo-Adjuvant Systemic Therapy in Locally Advanced Rectal Cancer
The addition of 5-fluorouracil (5-FU) or its prodrug capecitabine to radiotherapy (RT) is a standard approach in the neo-adjuvant treatment of patients with rectal tumors extending beyond the muscularis propria (stage II) and/or with clinical evidence of regional lymph node metastases (stage III). According to European randomized trials, the combined treatment modality resulted in favorable loc...
متن کاملOxaliplatin-based Neo-adjuvant Concurrent Chemo-radiotherapy in Treating Locally Advanced Lower Rectal Cancer
Taiwan and is a major cause of morbidity and mortality all over the world. Lower advanced rectal cancer, a challenge for surgeons, is problematic. Surgical therapy for rectal cancer has evolved since Ernest Miles first described the abdominoperineal resection in 1908. By the 1920s, he had reduced the recurrence rate from almost 100% to approximately 30%, thus ensuring this technique was the gol...
متن کاملPreoperative Chemoradiotherapy in Elderly Patients with Locally Advanced Rectal Cancer
PURPOSE To evaluate the treatment tolerance and clinical outcomes in patients aged 70 and older with locally advanced rectal carcinoma treated with multimodality approach. METHODS AND MATERIALS We retrospectively analysed 20 consecutive elderly patients, with histologically proven rectal adenocarcinoma, staged T3-4, and/or node-positive tumour, who received chemoradiotherapy and proceeded to ...
متن کاملNeoadjuvant concurrent chemoradiotherapy in treating locally advanced rectal cancer.
BACKGROUND Colorectal cancer is a common cancer and a major cause of morbidity and mortality worldwide. Middle to lower rectal cancer, a challenge for surgeons, is problematic. Neoadjuvant concurrent chemoradiotherapy (CCRT), introduced in the last decade, leads the local control of advanced rectal cancer to a high percentage of R0 resection (margin negative under microscopic examination) and a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Radiotherapy and Oncology
سال: 2016
ISSN: 0167-8140
DOI: 10.1016/s0167-8140(16)32543-9